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IRCE Begins 2nd Annual Scientific Symposium

Experts on Sickle Cell Disease and Cancers have converged to exchange ideas and promote collaborative efforts at the 2ND Annual Scientific Symposium of the International Research Center of Excellence (IRCE).

At the two-day symposium, the Dean of the University of Maryland School of Medicine, Baltimore, USA, Dr. Mark Gladwin, said that Nigeria has the most babies born with Sickle Cell Disease than any country of the world.

Dr Gladwin, an expert in Sickle Cell Disease and Pulmonary Hypertension, added that “Often, Sickle Cell Disease is put on lower priority than HIV, malaria and tuberculosis because Africa faces many infectious health challenges. In the same way that we see that HIV is controlled with medications, medications are being developed for sickle cell. What is important is to identify a baby with sickle cell early.”

He recommended the use of hydroxyurea to reduce the damaging effects of sickle cell on organs and prevent complications that may occur in adulthood.

“Hydroxyurea has a very big effect. It improves survival and reduces painful attacks and organ damage. It is not a cure but it makes a significant impact,” the Dean said.

He noted that with the progress of science, more new therapies are being developed for sickle cell disease.

Dr. Gladwin said that the University of Maryland ‘s long standing partnership with Nigeria through the Institute of Human Virology Nigeria (IHVN) in HIV, tuberculosis and malaria will be leveraged upon to address non-communicable diseases like cancer, hypertension and sickle cell disease.

Earlier, IHVN Chief Executive Officer, Dr. Patrick Dakum welcomed both local and international experts to the symposium and said that the Institute is expanding its partnerships among public, private and faith-based organizations.

“In terms of partnerships, ever since we started in 2024, we engaged both the public and private sector. In terms of the grants that we are currently implementing with several actors, we are seeking partnerships with both local and international institutions,” Dr Dakum said.

IRCE Executive Director, Prof. Alash’le Abimiku expressed optimism that the meeting will foster relationships to drive scientific innovation and progress. She said the center will continually strive to be “a fertile ground for discovery, collaboration and development of young talents, while promoting ethical conduct of research for the benefit of local and international communities.”

IHVN Celebrates July Employees of the Month

In fostering an excellent work culture and staff performance, the Executive Management of the Institute of Human Virology Nigeria (IHVN) has initiated the “Employee Recognition Awards” to recognise “Employees of the Month” and “Employee of the Year.”

According to the IHVN Director of Finance and Administration, Mr. Olu Alabi, this recognition covers overall employee performance in dressing, innovation, teamwork, productivity, efficiency, leadership & interpersonal skills, punctuality and adherence to company values and principles amongst others.

For July 2024, IHVN Celebrates, Zayyan Bello, Temitope Olukomogbon, Judith Arachie, Adeyemo Adeyemi, Chieme Ogumka, Chigozie Ezinne Nwafor, Nakom Kefas, Pantong Gershon Daskyakar, Fredrick Saiki, Yop Tenmang, whose performance stood out in their teams.

Three hearty cheers to our July star performers!

IRCE-IHVN Set to Host Symposium on Cancer and Sickle Cell Disease

The International Research Center of Excellence (IRCE) at the Institute of Human Virology Nigeria (IHVN) is set to host its 2nd Annual Scientific Symposium on “Expanding Partnerships to Sickle Cell Disease (SCD) and Cancer Research” from August 14th to 15th at the IHVN Campus in Abuja.

The two-day event will feature extensive presentations and discussions on health research in sickle cell disease and cancer and will include the diagnosis, care, treatment, and innovative applied research. The two-day symposium will bring together local and international experts such as the Dean of the University of Maryland School of Medicine (UMB-SOM), Prof. Mark T. Gladwin, and Executive Director of the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center (UMGCCC), Prof. Taofeek K. Owonikoko who are accompanied by several senior faculty from UMB-SOM already involved in research activities in Nigeria.

Nigerian experts such as Dr. Obi Adigwe DG NIPRD, Prof Obigelli Nnodu and Dr. Paul Jibrin from AUTH, Dr Tola Adewole from NSIA, and several representatives from pharma and industry will also participate as speakers. Industrial partners will also have exhibitions booths.

Special Guest at the symposium, Dean Gladwin is an expert in pulmonary hypertension and sickle cell disease (SCD), Prof Gladwin’s research identified a novel disease mechanism, named hemolysis-associated endothelial dysfunction that brought attention to the resistance to nitric oxide in patients with diseases like sickle cell and, malaria. His studies on hemolysis-associated endothelial dysfunction have enabled the clinical and epidemiological characterization of a human disease syndrome known as hemolysis-associated pulmonary hypertension which poses a significant risk to patients with sickle cell anemia. He is currently heading a Phase II clinical trial, conducted across 22 sites in France, Brazil, and the U.S which aims to evaluate the effectiveness of a novel blood transfusion technique that utilizes the patient’s blood to improve outcomes and extend survival in patients with sickle cell disease.

Nigerian-born Prof. Taofeek K. Owonikoko is a distinguished physician and scientist with a specialty in thoracic oncology and translational research. Prof. Owonikoko is the lead oncologist for the University of Maryland School of Medicine (UMSOM) and the University of Maryland Medical Center (UMMC).

IHVN CEO, Dr. Patrick Dakum pointed out that “this year also marks a significant milestone for IHVN as it celebrates its 20th anniversary. Over the past two decades, IHVN has made remarkable strides in HIV/AIDS, TB, and malaria through its two centers – the Center for Public Health Implementation (CPHI) and IRCE; and through strategic collaborations with the government of Nigeria, UMB-SOM and Institute of Human Virology (IHV) Baltimore- IHVN’s initial parent institution, and other institutions. We are excited to continue to extend such fruitful partnership to other key public health diseases such as SCD and Cancer.”

IRCE Executive Director, Prof. Alash’le Abimiku said that since 2016, IRCE has leveraged on CPHI’s extensive programmatic experience and infrastructure to advance IHVN’s research agenda. It’s state of the art core laboratories, biorepository, clinical trial unit, and core of well-trained research staff have facilitated the conduct of ethically and culturally acceptable high-quality research, thus enabling the institution to provide data and evidence required to improve health care and ensure pandemic preparedness.

IRCE is one of the centers at IHVN. It was established in 2015 to promote public/private partnerships for quality research with capacity building. IRCE has been pivotal in pioneering innovative research toward improving healthcare services and building research capacity among young Nigerian investigators. The Center is implementing more than 40 funded research grants in infectious and non-infectious diseases in Nigeria to address local and global health challenges.

According to Prof Abimiku, “This second IRCE symposium builds on the first which was held last year, focused on ‘Addressing Local Health Challenges through Quality Research and Partnerships’ by extending collaboration to two important health challenges that targets the black population – SCD and Cancers. The symposium will be held yearly as an avenue to promote research on issues of public health relevance to Nigeria and the world and will continue to involve the government, research institutions, and our private and industry partners,”

Stakeholders Commit to Integration of TB&HIV Services

More than 200 experts from the Federal and State Ministries of Health, non-governmental organizations, international organizations, and funders have reaffirmed their commitment to prioritizing the integration of tuberculosis (TB) and HIV programs across the 36 states of the country and the Federal Capital Territory.

This commitment was reinforced during a five-day National Boot Camp hosted by the Institute of Human Virology Nigeria (IHVN) in Lagos State. The camp focused on discussing the integration of TB and HIV services to enhance healthcare delivery under the Global Fund Grant Cycle 7.

The experts reached a consensus to harmonize service delivery and reporting across TB and HIV implementers nationwide, with plans to evaluate progress at three and six-month intervals.

Dr. Aderonke Agbaje, IHVN Director of Programs – Special Projects, emphasized, “Integration increases the impact of interventions. It makes us more effective in implementation. As a Principal Recipient of the Global Fund Grant Cycle 7 project, IHVN is working under the leadership of the Directorate of Public Health, National Tuberculosis, Buruli Ulcer and Leprosy Control Programme (NTBLCP), National AIDS and STD Control Program (NASCP), and the National Agency for the Control of AIDS (NACA) to bolster Nigeria’s response to the epidemics of tuberculosis and HIV in the public and private sectors and the community.”

The Boot Camp featured engaging break-out and brainstorming sessions on the treatment and care cascade for HIV and TB, monitoring and evaluation requirements, and TB/HIV health and non-health product management. Additionally, guidelines and standard operating procedures were developed for HIV Testing Services among presumed pregnant women outside conventional health facilities.

Key attendees included the Director of Public Health, Dr. Chukwuma Anyaike; the Director of Health Planning, Research, and Statistics, Dr. Chris Isokpunwu; Representative of the Health Commissioners Forum, Hon. Commissioner of Health for Kwara State, Dr. Amina M. Ahmed El-Imam; and representatives from the Global Fund, PEPFAR, USAID, UNAIDS, UNODC, the Network of People Living with HIV (NEPWHAN), and the Country Coordinating Mechanism (CCM). These leaders called for collective action and the support of all stakeholders in achieving TB and HIV integration and building sustainable and resilient health systems.

IHVN Sensitizes FCT Communities on Gender-Based Violence

The Institute of Human Virology Nigeria (IHVN) has sensitized Iddo Padda and Gwagwa communities in the Federal Capital Territory on gender-based violence(GBV).
The sensitization program involved advocacy to community leaders, a road walk within the community market and health checks.

IHVN Senior Program Officer Prevention, Care and Treatment, Mrs. Derby Collins-Kalu says that the Institute in collaboration with New Hope Agency, a community-based organization, organized the activity in these communities to prevent GBV and rape.

“The program reports we are getting from the community shows a high rate of gender-based violence, especially rape for minors. We work with health facilities to sensitize women during immunization. Rape is the most common in these communities. We presented these findings to the community leaders. The sensitization activity is to tell the people what is happening in their community and stimulate behaviour change in the areas of rape. We also want to educate people about rape and to tell them the services available to someone who has been raped in the health care center.”

Mrs, Collins-Kalu explains that timely presentation of  persons who experience rape in health facilities makes the difference.  

“This event is part of a broader effort to sensitize the community about the realities of  GBV.. IHVN has been educating residents on recognizing signs of rape, understanding the available care pathways, and emphasizing the importance of timely medical intervention. Immediate medical attention is critical to prevent the transmission of HIV, manage potential pregnancies, address sexually transmitted diseases, and mitigate the emotional trauma associated with rape.”

New Hope Agency GBV Program Manager, Ifeoma Okonkwo says that “Our collaboration with IHVN has been instrumental in bringing awareness to the community. Engaging with the public has brought a noticeable increase in community participation and willingness to discuss GBV issues.”

Mrs Okonkwo lamented the culture of silence in the society that makes people hesitant to speak about GBV. .

“Most of the cultures are very abusive, I also believe that if we can sensitize our communities, they will speak out.”

Women who received testing services during the sensitization program expressed appreciation for the activity. 22-year-old housewife, Sekinah Ilasu says, “I am grateful for this initiative to tell women to speak up about Gender Based Violence because a lot of people in our community today are facing violence from their husbands and they are afraid to speak up because it will only make the situation worst.”

Another participant, a petty trader, Zainab Daro, called for participation of men in sensitization programs too.  “I wish our husbands were here to hear this so that those who beat their wives can know that it is bad and stop,”